Myers Science Hub | Real 3D Protein Structures

Examine experimentally determined molecular structures from the Protein Data Bank (PDB). Rotate, zoom and explore the protein using the interactive RCSB PDB molecular viewer. These are real atomic-coordinate models, not schematic drawings.

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Crambin (PDB: 1CRN)

A small protein whose experimentally determined atomic coordinates show a folded polypeptide. Look for the overall tertiary structure.

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AP Biology exploration prompts

  1. Locate alpha helices and beta sheets, where present. Which interactions stabilize these secondary structures?
  2. Explain how the sequence of amino acids (primary structure) influences the overall fold (tertiary structure).
  3. Compare ubiquitin with hemoglobin. What distinguishes tertiary from quaternary structure?
  4. Why might a change in pH or temperature disrupt a protein's structure and function?